Dermafit
Retinoid Trifecta Cream
Retinoid Trifecta Cream
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Retinoid Trifecta Cream
Three Retinoids. One Purpose. Maximum Results, Minimal Irritation.
Retinoid Trifecta is a dermatologically engineered cream featuring a triple-retinoid system that delivers multi-level cellular activation without the harsh side effects of conventional retinoids. This innovative hybrid combines Hydroxypinacolone Retinoate (HPR), Retinol, and Retinyl Palmitate, encapsulated within a staggered-release delivery matrix that supports gradual penetration, reduced inflammation, and enhanced skin tolerance.
Scientific Complex & Key Retinoids
✓ Hydroxypinacolone Retinoate (1%) – Direct-Acting Retinoid
A next-generation retinoid that binds directly to retinoid receptors—requiring no metabolic conversion—for prescription-level performance without the irritation. Clinically shown to stimulate fibroblast activity, boost collagen production, and regulate pigmentation at a dermal level.
✓ Retinol (0.5%) – Classic Vitamin A Molecule
Proven to accelerate cellular turnover, refine texture, and reduce fine lines and acne. Converts to retinoic acid in two steps, offering deep epidermal renewal with balanced performance.
✓ Retinyl Palmitate (0.5%) – Gentle Precursor
A vitamin A ester with antioxidant benefits, converted through three metabolic steps. Acts as a supportive reservoir for long-term skin health and barrier repair, making this trifecta ideal for those new to high-strength retinoids.
✓ Dimethyl Isosorbide (DMI) – Precision Delivery Agent
Enhances solubility and dermal penetration of actives for controlled delivery, ensuring retinoid stability and reduced skin irritation during overnight absorption.
✓ Squalane & Caprylic/Capric Triglyceride
Replenish lipids, reinforce the skin barrier, and reduce dryness and flaking commonly associated with retinoid therapy.
Clinical Benefits
✓ Stimulates collagen production and dermal remodeling
✓ Improves uneven pigmentation and sun damage
✓ Refines pore size, rough texture, and surface dullness
✓ Targets hormonal and inflammatory acne
✓ Minimizes retinoid-related irritation through slow-release delivery
Indications
✓ Early to advanced signs of aging (fine lines, loss of firmness)
✓ Acne-prone or photo-damaged skin
✓ Safe for Fitzpatrick I–IV (with proper use)
✓ Ideal for nighttime use in resistance or Skin HIIT phases of your DermaFit system
How to Use
Apply a pea-sized amount in the evening to clean, dry skin. Begin 2–3 times per week and increase as tolerated. Always follow with a barrier-repair serum or moisturizer and wear broad-spectrum SPF daily. Avoid combining with exfoliating acids on the same night unless professionally guided.
Why You’ll Love It
Retinoid Trifecta is not just another retinol cream—it’s a clinical powerhouse combining three generations of vitamin A derivatives into a single, stabilized, time-release treatment. It delivers deep transformation with significantly less peeling, burning, or flaking—making it suitable for progressive clients seeking real results without the downtime.
Full INCI List
Water (Aqua), Caprylic/Capric Triglyceride, Methylpropanediol, Dicaprylyl Carbonate, C12-15 Alkane, Cetearyl Alcohol, Cetearyl Glucoside, Squalane, Polyacrylamide (and) C13-14 Isoparaffin, Xanthan Gum, Caprylyl Glycol, Retinol, Laureth-7, Tocopherol, Disodium EDTA, Retinyl Palmitate, Dimethyl Isosorbide, Hydroxypinacolone Retinoate, Polysorbate 20, Phenylpropanol, Propanediol, Phenoxyethanol, Ethylhexylglycerin.
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