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Dermafit

RetinoLogic Peptide Serum

RetinoLogic Peptide Serum

Regular price R 1,950.00 ZAR
Regular price Sale price R 1,950.00 ZAR
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Retino-Logic – Matrix Reform Serum

Rebuild • Restructure • Resurface
Intelligent Retinoid Therapy + Dermal Matrix Repair

Retino-Logic is a next-generation retinoid-alternative serum designed to deliver the transformative benefits of retinoids without irritation. This scientifically formulated treatment supports collagen synthesis, skin renewal, and matrix remodeling, making it ideal for sensitive skin, retinoid beginners, and those recovering from intensive treatments. With a synergistic blend of Niacinamide, Copper Peptides, Silybin (from milk thistle), and Sodium Hyaluronate, it enhances elasticity, clarity, and tone while supporting the skin’s repair systems.


Key Scientific Complex

Silybin (Milk Thistle Extract)
A natural antioxidant compound shown to inhibit MMPs (matrix metalloproteinases) that break down collagen and elastin. Enhances dermal matrix stability and reduces inflammation-induced degradation.

Niacinamide (Vitamin B3)
Clinically proven to reduce pigmentation, enhance barrier function, and suppress excess sebum. Supports repair of damaged skin while boosting resilience to environmental stress.

Copper Lysinate/Prolinate (Copper Tripeptide Complex)
A bioavailable copper delivery system that accelerates wound healing, stimulates fibroblast activity, and promotes collagen and elastin production at a cellular level.

Sodium Hyaluronate
A low-molecular-weight hyaluronic acid that delivers deep hydration and improves skin elasticity and plumpness.

Bisabolol & Shea Butter
Soothing and anti-inflammatory emollients that reduce redness and calm sensitivity, making this formula suitable for compromised or reactive skin.


Clinical Benefits

✓ Promotes collagen remodeling and matrix density
✓ Reduces inflammation and supports dermal healing
✓ Brightens uneven skin tone and refines texture
✓ Increases skin resilience and hydration retention
✓ A non-irritating alternative to traditional retinoids


Indications

✓ Ideal for sensitive, post-procedure, or retinoid-intolerant skin
✓ Fine lines, sagging, texture irregularities, and dullness
✓ Supports recovery after peels, lasers, or microneedling
✓ Fitzpatrick I–VI compatible


How to Use

✓ Apply once or twice daily to clean skin before moisturiser
✓ Use alone or alternate with stronger actives on “rest” nights
✓ Compatible with other serums, peptides, or SPF in morning routines
✓ Can be introduced immediately post-treatment (if skin barrier is intact)


Why You’ll Love It

Retino-Logic brings intelligent skin repair to the forefront. Designed for clients who seek dermal transformation without inflammation, it’s perfect for pre-conditioning, post-treatment support, or year-round use in sensitive or rosacea-prone skin. Think of it as retinoid logic without the retinoid reaction—powerful, precise, and universally tolerable.


Clinically Proven Results: Silybin Phytosome vs. Retinol & Bakuchiol

Based on an 8-week (56-day) clinical trial conducted on 60 volunteers using 0.8% Silybin Phytosome (your formulation contains 1%), the following outcomes were observed:

+23% increase in Collagen Type III compared to Bakuchiol and +16% vs. Retinol (0.2%)
+14% increase in Collagen Type I vs. Bakuchiol
+36% more Hyaluronic Acid production than Bakuchiol (on par with Retinol)
2.3× reduction in wrinkle depth compared to placebo
24.3% reduction in forehead wrinkle count vs. placebo
22.9% less redness than Retinol
9.1% increased hydration compared to Retinol
0% irritation vs. 42.9% irritation with Retinol


Why It Outperforms

Retino-Logic uses Silybin, the active antioxidant compound in Milk Thistle, paired with Phytosome™ Technology to enhance absorption and skin affinity. This botanical retinoid alternative delivers results equivalent to clinical-grade retinol—but without the redness, dryness, or barrier disruption.

Unlike Bakuchiol, Silybin has been shown to increase dermal collagen and hyaluronic acid levels across multiple layers of the skin, leading to firmer, more hydrated, and visibly smoother skin—with excellent tolerance even in sensitive skin types.

Full INCI List

Water, Pentylene Glycol, Glycerin, Isopropyl Myristate, Caprylic/Capric Triglyceride, Squalane, Butyrospermum Parkii (Shea) Butter, Cetearyl Wheat Straw Glycosides, Niacinamide, PEG-12 Dimethicone, Glycereth-26, Cetearyl Ethylhexanoate, Propylene Glycol, Silybin, Bisabolol, Copper Lysinate/Prolinate, Sodium Hyaluronate, Methylglucoside Phosphate, Tocopheryl Acetate (Vitamin E), Lecithin, Cetearyl Alcohol, Polymethylsilsesquioxane, Isohexadecane, Phenoxyethanol, Ammonium Acryloyldimethyltaurate/VP Copolymer, Stearic Acid, PEG-40 Stearate, Sodium Acryloyldimethyl Taurate Copolymer, Cetearyl Methicone, Ethylhexylglycerin, C13-C15 Alkane, Disodium EDTA, Steareth-2, Synthetic Fluorphlogopite, Steareth-21, Rhizobian Gum, Coco-Glucoside, Titanium Dioxide (CI 77891), Magnesium Silicate, Chlorphenesin.

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